School of Surgery

Cartilage Regeneration

With the fast development of cell based therapies and biomaterials for the repair and regeneration of articular cartilage, the research application (both underway and proposed) continues to increase exponentially.

With techniques such as Matrix-induced Autologous Chondrocyte Implantation (MACI) now an established method of cartilage regeneration, and considered ‘gold-standard’ in the repair of articular cartilage defects, research for this and other associated technologies will continue to prosper.


This research aims to optimise patient and graft outcomes through a number of important, though inter-related activities, such as:

  • Improving surgical techniques – the general ACI procedure continues to evolve, though ongoing research is needed to develop current methods. Arthroscopic MACI has emerged as an innovative and exciting surgical technique, with improved early patient outcomes.
  • Improving cell culturing methods – research into the development of biomaterials and cell culturing methods is of the upmost importance to this department, and good quality tissue repair.
  • Optimising the application of pre- and post-operative rehabilitation – an important factor in patient and graft outcome, though relatively untouched by good quality research; this department is leading the way internationally in the development of rehabilitation protocols.

This Page

Last updated:
Wednesday, 16 September, 2009 10:22 AM